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The antibody against CACNB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CACNB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05494A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CACNB3 |
| Target Synonyms | CAB3; CACNLB3; CACNB3 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | VYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDSY | Uniprot ID | P54284 |
Uniprot Id
P54284
Target Species
Human
Target Name
CACNB3
Target Full Name
Voltage-dependent L-type calcium channel subunit beta-3
Target Function
Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Calcium channel beta subunit family
Target Tissue Specificity
Expressed mostly in brain, colon and ovary.
Target Synonyms
CAB3; CACB3_HUMAN; Cacnb3; CACNLB3; Calcium channel voltage dependent beta 3 subunit; Calcium channel voltage-dependent subunit beta 3; FLJ58949; Voltage-dependent L-type calcium channel subunit beta-3
Target Background
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
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