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Rabbit anti-Human CACNB3 Polyclonal Antibody

The antibody against CACNB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05494A

The antibody against CACNB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05494A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCACNB3
Target SynonymsCAB3; CACNLB3; CACNB3FormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2).Target SpeciesHuman
Immunogen SequenceVYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDSYUniprot IDP54284
Background Information
  • Uniprot Id

    P54284

  • Target Species

    Human

  • Target Name

    CACNB3

  • Target Full Name

    Voltage-dependent L-type calcium channel subunit beta-3

  • Target Function

    Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Calcium channel beta subunit family

  • Target Tissue Specificity

    Expressed mostly in brain, colon and ovary.

  • Target Synonyms

    CAB3; CACB3_HUMAN; Cacnb3; CACNLB3; Calcium channel voltage dependent beta 3 subunit; Calcium channel voltage-dependent subunit beta 3; FLJ58949; Voltage-dependent L-type calcium channel subunit beta-3

  • Target Background

    This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.

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