Rabbit anti-Human SMYD3 Polyclonal Antibody

The antibody against SMYD3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMYD3 (NP_001161212.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-05592A

Number

Cat.No	ADA-05592A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SMYD3
Target Synonyms	KMT3E; ZMYND1; ZNFN3A1; bA74P14.1; SMYD3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 22Rv1, HepG2, HT-29, MCF7, Mouse testis	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-05592A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SMYD3

Target Synonyms

KMT3E; ZMYND1; ZNFN3A1; bA74P14.1; SMYD3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 22Rv1, HepG2, HT-29, MCF7, Mouse testis

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMYD3 (NP_001161212.1).	Target Species	Human
Immunogen Sequence	DRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMT	Uniprot ID	Q9H7B4

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMYD3 (NP_001161212.1).

Target Species

Human

Immunogen Sequence

DRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMT

Uniprot ID

Q9H7B4

Background Information

Uniprot Id

Q9H7B4
Target Species

Human
Target Name

SMYD3
Target Full Name

Histone-lysine N-methyltransferase SMYD3
Target Function

Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Also methylates 'Lys-5' of histone H4. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.
Target Subcellular Location

Cytoplasm. Nucleus.
Target Protein Families

Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family
Target Tissue Specificity

Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas.
Target Research Area

Cancer
Target Synonyms

bA74P14.1 (novel protein); bA74P14.1; FLJ21080; histone lysine N methyltransferase SMYD3; KMT3E; MGC104324; SET and MYND domain containing 3; SET and MYND domain containing protein 3; SET and MYND domain-containing protein 3; SMYD 3; Smyd3; SMYD3 protein; SMYD3_HUMAN; Zinc finger MYND domain containing 1; Zinc finger MYND domain containing protein 1; Zinc finger MYND domain-containing protein 1; Zinc finger protein subfamily 3A MYND domain containing 1; Zinc finger protein, subfamily 3A (MYND domain containing), 1; ZMYND 1; ZMYND1; ZNFN3A1
Target Background

This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human SMYD3 Polyclonal Antibody

Specifications

Immunogen Information

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