Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SPDYA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SPDYA (NP_877433.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SPDYA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SPDYA (NP_877433.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06156A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPDYA |
| Target Synonyms | SPY1; SPDY1; RINGO3; RINGOA; SPDYA | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SPDYA (NP_877433.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5MJ70 | Immunogen Sequence |
Uniprot Id
Q5MJ70
Target Species
Human
Target Name
SPDYA
Target Full Name
Speedy protein A
Target Function
Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2.
Target Subcellular Location
Nucleus.
Target Protein Families
Speedy/Ringo family
Target Tissue Specificity
Highly expressed in testis. Expressed at a low level in wide range of tissues including bone marrow, brain, heart, kidney, colon, liver, placenta, spleen, skeletal muscle, salivary gland, thyroid gland, thymus, trachea and uterus. Expressed at a slightly
Target Synonyms
SPDYA; SPDY1; SPY1; Speedy protein A; Rapid inducer of G2/M progression in oocytes A; RINGO A; hSpy/Ringo A; Speedy-1; Spy1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
