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The antibody against Paxillin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Paxillin (NP_002850.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Paxillin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Paxillin (NP_002850.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07213A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Paxillin |
| Target Synonyms | Paxillin; PXN; paxillin | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | PC-3 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Paxillin (NP_002850.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNP | Uniprot ID | P49023 |
Uniprot Id
P49023
Target Species
Human
Target Name
PXN
Target Full Name
Paxillin
Target Function
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex.
Target Protein Families
Paxillin family
Target Synonyms
FLJ16691; FLJ23042; Paired box protein Pax 1; PAX 1; PAX1; PAXI_HUMAN; Paxillin alpha; Paxillin; PXN; PXN protein
Target Background
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
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