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The antibody against SP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-331 of human SP2 (NP_003101.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-331 of human SP2 (NP_003101.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07485A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SP2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. |
| Purification Method | Affinity purification | Positive Samples | HeLa, Jurkat, Mouse brain |
| Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 240-331 of human SP2 (NP_003101.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LSKTNKKARKKSLPASQPPVAVAEQVETVLIETTADNIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATL | Uniprot ID | Q02086 |
Uniprot Id
Q02086
Target Species
Human
Target Name
SP2
Target Full Name
Transcription factor Sp2
Target Function
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
Target Subcellular Location
Nucleus.
Target Protein Families
Sp1 C2H2-type zinc-finger protein family
Target Background
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
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