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The antibody against MRPL16 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human MRPL16(NP_060310.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MRPL16 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human MRPL16(NP_060310.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08321A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL16 |
| Target Synonyms | L16mt; uL16m; MRP-L16; PNAS-111; MRPL16 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Hep G2 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MRPL16(NP_060310.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MWRLLARASAPLLRVPLSDSWALLPASAGVKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREPKNLSDIRGPSTEATEFTEGNFAILALGGGYLHWG | Uniprot ID | Q9NX20 |
Uniprot Id
Q9NX20
Target Species
Human
Target Name
MRPL16
Target Full Name
Large ribosomal subunit protein uL16m
Target Subcellular Location
Mitochondrion.
Target Protein Families
Universal ribosomal protein uL16 family
Target Synonyms
39S ribosomal protein L16; 39S ribosomal protein L16 mitochondrial; L16mt; mitochondrial; Mitochondrial ribosomal protein L16; MRP-L16; Mrpl16; PNAS 111; RM16_HUMAN
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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