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The antibody against NUDT6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 121-316 of human NUDT6 (NP_009014.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against NUDT6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 121-316 of human NUDT6 (NP_009014.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-08650A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUDT6 |
| Target Synonyms | GFG1; GFG-1; ASFGF2; FGF-AS; FGF2AS; NUDT6 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Jurkat | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 121-316 of human NUDT6 (NP_009014.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | DSSTLTLWLREGPSRLPGYASHQVGVAGAVFDESTRKILVVQDRNKLKNMWKFPGGLSEPEEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINFCQEECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGLFYKLYHKELPENYKTMKGID | Uniprot ID | P53370 |
Uniprot Id
P53370
Target Species
Human
Target Name
NUDT6
Target Full Name
Nucleoside diphosphate-linked moiety X motif 6
Target Function
May contribute to the regulation of cell proliferation.
Target Subcellular Location
Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms.
Target Protein Families
Nudix hydrolase family
Target Tissue Specificity
Detected in liver, kidney and esophagus (at protein level). Ubiquitous.
Target Synonyms
NUDT6; FGF2AS; Nucleoside diphosphate-linked moiety X motif 6; Nudix motif 6; EC 3.6.1.-; Antisense basic fibroblast growth factor; Protein GFG
Target Background
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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