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Rabbit anti-Human TSPAN4/NAG-2 Polyclonal Antibody

The antibody against TSPAN4/NAG-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human TSPAN4/NAG-2 (NP_003262.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09019A

The antibody against TSPAN4/NAG-2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human TSPAN4/NAG-2 (NP_003262.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09019A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTSPAN4/NAG-2
Target SynonymsNAG2; NAG-2; TM4SF7; TSPAN-4; TETRASPAN; TSPAN4/NAG-2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Mouse liver, Mouse lung, PC-3, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human TSPAN4/NAG-2 (NP_003262.1).Target SpeciesHuman
Immunogen SequenceIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPCYETVKVWLQEUniprot IDO14817
Background Information
  • Uniprot Id

    O14817

  • Target Species

    Human

  • Target Name

    TSPAN4

  • Target Full Name

    Tetraspanin-4

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Tetraspanin (TM4SF) family

  • Target Tissue Specificity

    Expressed in multiple tissues but is absent in brain, lymphoid cells, and platelets.

  • Target Synonyms

    TSPAN4; NAG2; TM4SF7; Tetraspanin-4; Tspan-4; Novel antigen 2; NAG-2; Transmembrane 4 superfamily member 7

  • Target Background

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

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