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The antibody against CDKN2AIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CDKN2AIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09810A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDKN2AIP |
| Target Synonyms | CARF; CDKN2AIP | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse thymus, Rat thymus, SKOV3 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NXV6 | Immunogen Sequence |
Uniprot Id
Q9NXV6
Target Species
Human
Target Name
CDKN2AIP
Target Full Name
CDKN2A-interacting protein
Target Function
Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
Target Subcellular Location
Nucleus, nucleoplasm.
Target Protein Families
CARF family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
Calcium response factor; CARF; CARF_HUMAN; CDKN2A interacting protein; CDKN2A-interacting protein; Cdkn2aip; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF; FLJ20036
Target Background
The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene.
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