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The antibody against TRIM31 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 186-425 of human TRIM31 (NP_008959.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TRIM31 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 186-425 of human TRIM31 (NP_008959.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10473A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRIM31 |
| Target Synonyms | RNF; HCG1; HCGI; C6orf13; TRIM31 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, Mouse large intestine, Mouse small intestine | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 186-425 of human TRIM31 (NP_008959.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BZY9 | Immunogen Sequence |
Uniprot Id
Q9BZY9
Target Species
Human
Target Name
TRIM31
Target Full Name
E3 ubiquitin-protein ligase TRIM31
Target Function
Regulator of Src-induced anchorage independent cell growth. May have E3 ubiquitin-protein ligase activity.
Target Subcellular Location
Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
Target Protein Families
TRIM/RBCC family
Target Tissue Specificity
Up-regulated in gastric adenocarcinomas.
Target Synonyms
TRIM31; C6orf13; RNF; E3 ubiquitin-protein ligase TRIM31; EC 2.3.2.27; RING-type E3 ubiquitin transferase TRIM31; Tripartite motif-containing protein 31
Target Background
This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants.
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