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The antibody against BDH1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-343 of human BDH1 (NP_004042.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against BDH1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-343 of human BDH1 (NP_004042.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11238A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BDH1 |
| Target Synonyms | BDH; SDR9C1; BDH1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, LO2, MCF7, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-343 of human BDH1 (NP_004042.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q02338 | Immunogen Sequence |
Uniprot Id
Q02338
Target Species
Human
Target Name
BDH1
Target Full Name
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Target Subcellular Location
Mitochondrion inner membrane. Mitochondrion matrix.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Target Research Area
Cancer
Target Synonyms
3 hydroxybutyrate dehydrogenase (heart; mitochondrial); 3-hydroxybutyrate dehydrogenase; BDH; BDH_HUMAN; BDH1; D beta hydroxybutyrate dehydrogenase; mitochondrial; D-beta-hydroxybutyrate dehydrogenase; mitochondrial
Target Background
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
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