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GATA3 Recombinant Monoclonal Antibody

The recombinant antibody against GATA3 was produced using a synthesized peptide derived from human GATA3 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.

ADC-56853A

The recombinant antibody against GATA3 was produced using a synthesized peptide derived from human GATA3 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.

$350.00

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Specifications


Cat.No ADC-56853A ClonalityMonoclonal
Target NameGATA3Target SynonymsGATA3, Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
FormLiquidSpecies ReactivityHuman
IsotypeRabbit IgGStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline
Purification MethodAffinity-chromatography purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionA synthesized peptide derived from human GATA3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP23771
Background Information
  • Uniprot Id

    P23771

  • Target Species

    Human

  • Target Name

    GATA3

  • Target Full Name

    Trans-acting T-cell-specific transcription factor GATA-3

  • Target Function

    Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression.

  • Target Involvement

    Hypoparathyroidism, sensorineural deafness, and renal disease (HDR)

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    T-cells and endothelial cells.

  • Target Synonyms

    GATA 3; GATA binding factor 3; GATA binding protein 3; GATA-binding factor 3; Gata3; GATA3_HUMAN; HDR; HDRS; MGC2346; MGC5199; MGC5445; Trans acting T cell specific transcription factor GATA 3; Trans-acting T-cell-specific transcription factor GATA-3

  • Target Background

    This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

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