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Rabbit anti-Human AGPS Polyclonal Antibody

The antibody against AGPS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 379-658 of human AGPS (NP_003650.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-09085A

The antibody against AGPS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 379-658 of human AGPS (NP_003650.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-09085A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAGPS
Target SynonymsADAS; ADPS; RCDP3; ADAP-S; ADHAPS; ALDHPSY; AGPSFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse kidney, HepG2, HL-60, K-562, Mouse lungApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 379-658 of human AGPS (NP_003650.1).Target SpeciesHuman
Uniprot IDO00116Immunogen Sequence
Background Information
  • Uniprot Id

    O00116

  • Target Species

    Human

  • Target Name

    AGPS

  • Target Full Name

    Alkyldihydroxyacetonephosphate synthase, peroxisomal

  • Target Function

    Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.

  • Target Involvement

    Rhizomelic chondrodysplasia punctata 3 (RCDP3)

  • Target Subcellular Location

    Peroxisome membrane. Peroxisome.

  • Target Protein Families

    FAD-binding oxidoreductase/transferase type 4 family

  • Target Synonyms

    AAG5; ADAP-S; ADAS; ADAS_HUMAN; ADHAPS; ADPS; Aging associated gene 5 protein; Aging-associated gene 5 protein; aging-associated protein 5; AGPS; ALDHPSY; Alkyl-DHAP synthase; Alkyldihydroxyacetonephosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkylglycerone phosphate synthase; Alkylglycerone-phosphate synthase; peroxisomal; RCDP3

  • Target Background

    This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

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