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The antibody against AK3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human AK3 (NP_057366.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AK3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human AK3 (NP_057366.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03906A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AK3 |
| Target Synonyms | AK6; FIX; AK3L1; AKL3L; AKL3L1; AK3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, 293T, A-549, BxPC-3, Mouse liver, Rat pancreas, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human AK3 (NP_057366.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UIJ7 | Immunogen Sequence |
Uniprot Id
Q9UIJ7
Target Species
Human
Target Name
AK3
Target Full Name
GTP:AMP phosphotransferase AK3, mitochondrial
Target Function
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Adenylate kinase family, AK3 subfamily
Target Tissue Specificity
Highly expressed in heart, skeletal muscle and liver, moderately expressed in pancreas and kidney, and weakly expressed in placenta, brain and lung.
Target Research Area
Metabolism
Target Synonyms
Adenylate kinase 3 alpha-like 1; Adenylate kinase 3; Adenylate kinase 3, formerly; adenylate kinase 6, adenylate kinase 3 like 1; AK 3; AK3; AK3, formerly; AK3L1; AK4; AK4, mouse, homolog of; AK6; AKL3L; AKL3L1; FIX; GTP:AMP phosphotransferase; GTP:AMP phosphotransferase, mitochondrial; KAD3_HUMAN; mitochondrial; OTTHUMP00000021015; OTTHUMP00000021016; RP11 6J24.4
Target Background
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.
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