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The antibody against AKAP14 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 70-150 of human AKAP14 (Q86UN6) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AKAP14 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 70-150 of human AKAP14 (Q86UN6) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-14284A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AKAP14 |
| Target Synonyms | AKAP28; PRKA14; AKAP14 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, DU-145, Mouse testis, Rat testis | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 70-150 of human AKAP14 (Q86UN6). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | HGEFTVEKGLKQIDEYFSKCVSKKCWAHGVEFVERKDLIHSFLYIYYVHWSISTADLPVARISAGTYFTMKVSKTKPPDAP | Uniprot ID | Q86UN6 |
Uniprot Id
Q86UN6
Target Species
Human
Target Name
AKAP14
Target Full Name
A-kinase anchor protein 14
Target Function
Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.
Target Synonyms
AKAP14; AKAP28A-kinase anchor protein 14; AKAP-14; A-kinase anchor protein 28 kDa; AKAP 28; Protein kinase A-anchoring protein 14; PRKA14
Target Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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