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The antibody against AMD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AMD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06840A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AMD1 |
| Target Synonyms | AMD; SAMDC; ADOMETDC; AMD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Mouse skeletal muscle, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P17707 | Immunogen Sequence |
Uniprot Id
P17707
Target Species
Human
Target Name
AMD1
Target Full Name
S-adenosylmethionine decarboxylase proenzyme
Target Function
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Target Protein Families
Eukaryotic AdoMetDC family
Target Synonyms
Adenosylmethionine decarboxylase 1; AdoMetDC; AMD1; DCAM_HUMAN; EC 4.1.1.50; FLJ26964; S adenosylmethionine decarboxylase 1; S adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase beta chain; SAMDC
Target Background
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.
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