Rabbit anti-Human ANP32E Polyclonal Antibody

The antibody against ANP32E was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09240A

Number

Cat.No	ADA-09240A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ANP32E
Target Synonyms	LANPL; LANP-L; ANP32E	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, K-562	Application	ELISA, WB

Cat.No

ADA-09240A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ANP32E

Target Synonyms

LANPL; LANP-L; ANP32E

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, K-562

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1).	Target Species	Human
Immunogen Sequence	MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLE	Uniprot ID	Q9BTT0

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1).

Target Species

Human

Immunogen Sequence

MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLE

Uniprot ID

Q9BTT0

Background Information

Uniprot Id

Q9BTT0
Target Species

Human
Target Name

ANP32E
Target Full Name

Acidic leucine-rich nuclear phosphoprotein 32 family member E
Target Function

Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
Target Subcellular Location

Cytoplasm. Nucleus.
Target Protein Families

ANP32 family
Target Tissue Specificity

Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
Target Synonyms

Acidic (leucine rich) nuclear phosphoprotein 32 family member E; Acidic leucine-rich nuclear phosphoprotein 32 family member E; AN32E_HUMAN; anp32e; Cerebellar postnatal development protein 1; LANP like protein; LANP-L; LANP-like protein; LANPL; Leucine rich acidic nuclear protein like; MGC5350
Target Background

Enables histone binding activity. Involved in histone exchange. Located in nucleus. Part of Swr1 complex.

Rabbit anti-Human ANP32E Polyclonal Antibody

Specifications

Immunogen Information

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