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The antibody against ANXA13 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human ANXA13 (NP_004297.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ANXA13 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human ANXA13 (NP_004297.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-06083A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ANXA13 |
| Target Synonyms | ISA; ANX13; ANXA13 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, LO2, Mouse small intestine, Rat small intestine | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human ANXA13 (NP_004297.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P27216 | Immunogen Sequence |
Uniprot Id
P27216
Target Species
Human
Target Name
ANXA13
Target Full Name
Annexin A13
Target Function
Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup.; Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium.
Target Subcellular Location
Apical cell membrane. Cell membrane; Lipid-anchor. Cytoplasmic vesicle.
Target Protein Families
Annexin family
Target Tissue Specificity
Detected in epithelial cells in colon and jejunum (at protein level). Detected in epithelial cells in jejunum.
Target Synonyms
Annexin A13; Annexin XIII; Annexin; intestine-specific; Annexin-13; ANX 13; ANX A13; ANX13; ANX13_HUMAN; ANXA13; Intestine Specific Annexin; Intestine-specific annexin; ISA; MGC150460
Target Background
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.
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