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The antibody against APOBEC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against APOBEC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07349A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APOBEC2 |
| Target Synonyms | ARP1; ARCD1; APOBEC2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Rat heart, Mouse skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human APOBEC2 (NP_006780.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y235 | Immunogen Sequence |
Uniprot Id
Q9Y235
Target Species
Human
Target Name
APOBEC2
Target Full Name
C->U-editing enzyme APOBEC-2
Target Function
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Target Protein Families
Cytidine and deoxycytidylate deaminase family
Target Tissue Specificity
Expressed exclusively in heart and skeletal muscle.
Target Synonyms
APOBEC2C->U-editing enzyme APOBEC-2; EC 3.5.4.36; mRNA(cytosine(6666)) deaminase 2
Target Background
Enables cytidine deaminase activity and identical protein binding activity. Involved in DNA demethylation. Acts upstream of or within cytidine to uridine editing. Predicted to be active in cytoplasm and nucleus.
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