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Rabbit anti-Human ARHGAP1 Polyclonal Antibody

The antibody against ARHGAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 210-439 of human ARHGAP1 (NP_004299.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-04074A

The antibody against ARHGAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 210-439 of human ARHGAP1 (NP_004299.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

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Specifications


Cat.No ADA-04074A ClonalityPolyclonal
Host SpeciesRabbitTarget NameARHGAP1
Target SynonymsRHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP; ARHGAP1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, BxPC-3, HepG2, Mouse lung, PC-12, U-87MGApplicationELISA, WB, IP

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 210-439 of human ARHGAP1 (NP_004299.1).Target SpeciesHuman
Uniprot IDQ07960Immunogen Sequence
Background Information
  • Uniprot Id

    Q07960

  • Target Species

    Human

  • Target Name

    ARHGAP1

  • Target Full Name

    Rho GTPase-activating protein 1

  • Target Function

    GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    RHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP; ARHGAP1

  • Target Background

    This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.

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