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Rabbit anti-Human ATF3 Polyclonal Antibody

The antibody against ATF3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ATF3 (NP_001665.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06225A

The antibody against ATF3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ATF3 (NP_001665.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06225A ClonalityPolyclonal
Host SpeciesRabbitTarget NameATF3
Target SynonymsATF3FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, RAW264.7, RAW264.7+LPSApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ATF3 (NP_001665.1).Target SpeciesHuman
Immunogen SequenceMMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQSUniprot IDP18847
Background Information
  • Uniprot Id

    P18847

  • Target Species

    Human

  • Target Name

    ATF3

  • Target Full Name

    Cyclic AMP-dependent transcription factor ATF-3

  • Target Function

    This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTActivates transcription presumably by sequestering inhibitory cofactors away from the promoters.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, ATF subfamily

  • Target Research Area

    Cancer

  • Target Synonyms

    Activating transcription factor 3; ATF3; ATF3_HUMAN; ATF3deltaZip2; ATF3deltaZip2c; ATF3deltaZip3; cAMP dependent transcription factor ATF3; cAMP-dependent transcription factor ATF-3; Cyclic AMP dependent transcription factor ATF3; Cyclic AMP-dependent transcription factor ATF-3

  • Target Background

    This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.

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