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The antibody against ATP13A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 880-960 of human ATP13A1 (NP_065143.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ATP13A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 880-960 of human ATP13A1 (NP_065143.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05956A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATP13A1 |
| Target Synonyms | ATP13A; CGI-152; ATP13A1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 880-960 of human ATP13A1 (NP_065143.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | ALLANAPERVVERRRRPRDSPTLSNSGIRATSRTAKQRSGLPPSEEQPTSQRDRLSQVLRDLEDESTPIVKLGDASIAAPF | Uniprot ID | Q9HD20 |
Uniprot Id
Q9HD20
Target Species
Human
Target Name
ATP13A1
Target Full Name
Endoplasmic reticulum transmembrane helix translocase
Target Function
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Cation transport ATPase (P-type) (TC 3.A.3) family, Type V subfamily
Target Synonyms
ATP13A1; ATP13A; KIAA1825; CGI-152Manganese-transporting ATPase 13A1; EC 7.2.2.-
Target Background
Enables transmembrane protein dislocase activity. Involved in extraction of mislocalized protein from ER membrane. Located in membrane.
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