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The antibody against BHMT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 177-406 of human BHMT (NP_001704.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against BHMT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 177-406 of human BHMT (NP_001704.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02210A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BHMT |
| Target Synonyms | BHMT1; HEL-S-61p; BHMT | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Rat liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 177-406 of human BHMT (NP_001704.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q93088 | Immunogen Sequence |
Uniprot Id
Q93088
Target Species
Human
Target Name
BHMT
Target Full Name
Betaine--homocysteine S-methyltransferase 1
Target Function
Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Found exclusively in liver and kidney.
Target Synonyms
Betaine homocysteine methyltransferase; Betaine homocysteine S methyltransferase 1; Betaine homocysteine S methyltransferase; Betaine--homocysteine S-methyltransferase 1; BHMT; BHMT1; BHMT1_HUMAN; EC 2.1.1.5; Epididymis secretory sperm binding protein Li 61p; HEL S 61p
Target Background
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
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