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The antibody against BLVRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against BLVRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-02607A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BLVRB |
| Target Synonyms | FLR; BVRB; SDR43U1; HEL-S-10; BLVRB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | U-251MG, U-87MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P30043 | Immunogen Sequence |
Uniprot Id
P30043
Target Species
Human
Target Name
BLVRB
Target Full Name
Flavin reductase (NADPH)
Target Function
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
Target Synonyms
Biliverdin IX beta reductase; biliverdin reductase B (flavin reductase (NADPH)); Biliverdin reductase B; Biliverdin-IX beta-reductase; BLVRB; BLVRB_HUMAN; BVR B; BVR-B; BVRB; epididymis secretory protein Li 10; Flavin reductase (NADPH); Flavin reductase; FLR; FR; GHBP; Green heme binding protein; Green heme-binding protein; HEL-S-10; Methemoglobin reductase; MGC117413; NADPH dependent diaphorase; NADPH flavin reductase; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U; member 1
Target Background
Enables biliverdin reductase (NAD(P)+) activity and riboflavin reductase (NADPH) activity. Involved in heme catabolic process. Located in cytosol; nucleoplasm; and plasma membrane.
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