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Rabbit anti-Human BLVRB Polyclonal Antibody

The antibody against BLVRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-02607A

The antibody against BLVRB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-02607A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBLVRB
Target SynonymsFLR; BVRB; SDR43U1; HEL-S-10; BLVRBFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesU-251MG, U-87MGApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human BLVRB (NP_000704.1).Target SpeciesHuman
Uniprot IDP30043Immunogen Sequence
Background Information
  • Uniprot Id

    P30043

  • Target Species

    Human

  • Target Name

    BLVRB

  • Target Full Name

    Flavin reductase (NADPH)

  • Target Function

    Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.

  • Target Synonyms

    Biliverdin IX beta reductase; biliverdin reductase B (flavin reductase (NADPH)); Biliverdin reductase B; Biliverdin-IX beta-reductase; BLVRB; BLVRB_HUMAN; BVR B; BVR-B; BVRB; epididymis secretory protein Li 10; Flavin reductase (NADPH); Flavin reductase; FLR; FR; GHBP; Green heme binding protein; Green heme-binding protein; HEL-S-10; Methemoglobin reductase; MGC117413; NADPH dependent diaphorase; NADPH flavin reductase; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U; member 1

  • Target Background

    Enables biliverdin reductase (NAD(P)+) activity and riboflavin reductase (NADPH) activity. Involved in heme catabolic process. Located in cytosol; nucleoplasm; and plasma membrane.

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