Rabbit anti-Human BRD3 Polyclonal Antibody

The antibody against BRD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-305 of human BRD3 (NP_031397.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-09889A

Number

Cat.No	ADA-09889A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	BRD3
Target Synonyms	ORFX; FSHRG2; RING3L; BRD3	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, BT-474, DU145, HepG2, Jurkat	Application	ELISA, WB, IHC-P

Cat.No

ADA-09889A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

BRD3

Target Synonyms

ORFX; FSHRG2; RING3L; BRD3

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, BT-474, DU145, HepG2, Jurkat

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 150-305 of human BRD3 (NP_031397.1).	Target Species	Human
Immunogen Sequence	PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKK	Uniprot ID	Q15059

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 150-305 of human BRD3 (NP_031397.1).

Target Species

Human

Immunogen Sequence

PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKK

Uniprot ID

Q15059

Background Information

Uniprot Id

Q15059
Target Species

Human
Target Name

BRD3
Target Full Name

Bromodomain-containing protein 3
Target Function

Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.
Target Involvement

A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Ubiquitous.
Target Synonyms

BRD 3; Brd3; BRD3_HUMAN; Bromodomain containing 3; Bromodomain containing protein 3; Bromodomain-containing protein 3; KIAA0043 ; Open reading frame X; ORFX; RING3 like gene; RING3-like protein; RING3L
Target Background

This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

Rabbit anti-Human BRD3 Polyclonal Antibody

Specifications

Immunogen Information

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