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The antibody against BRPF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against BRPF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-04481A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BRPF1 |
| Target Synonyms | BR140; IDDDFP; BRPF1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MGVDFDVKTFCHNLRATKPPYECPVETCRKVYKSYSGIEYHLYHYDHDNPPPPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRKDSNHHHHHNVSASTTPKLPEVVYRELEQDTPDAPPRPTSYYR | Uniprot ID | P55201 |
Uniprot Id
P55201
Target Species
Human
Target Name
BRPF1
Target Full Name
Peregrin
Target Function
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2.
Target Involvement
Intellectual developmental disorder with dysmorphic facies and ptosis (IDDDFP)
Target Subcellular Location
Nucleus. Chromosome. Cytoplasm.
Target Tissue Specificity
High levels in testis.
Target Synonyms
BR140; Bromodomain and PHD finger containing 1; Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein; 140kD ; BRPF1; BRPF1_HUMAN; Peregrin; Protein Br140
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