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The antibody against C12orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, ELISA.
The antibody against C12orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, ELISA.
Immunohistochemistry analysis of C12orf10 in paraffin-embedded rat testis using C12orf10 Rabbit pAb at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
| Cat.No | ADA-02304A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C12orf10 |
| Target Synonyms | MYG; Gamm1; MST024; MSTP024; C12orf10 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 48-376 of human C12orf10 (NP_067653.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9HB07 | Immunogen Sequence |
Uniprot Id
Q9HB07
Target Species
Human
Target Name
MYG1
Target Full Name
MYG1 exonuclease
Target Function
3'-5' RNA exonuclease which cleaves in situ on specific transcripts in both nucleus and mitochondrion. Involved in regulating spatially segregated organellar RNA processing, acts as a coordinator of nucleo-mitochondrial crosstalk. In nucleolus, processes pre-ribosomal RNA involved in ribosome assembly and alters cytoplasmic translation. In mitochondrial matrix, processes 3'-termini of the mito-ribosomal and messenger RNAs and controls translation of mitochondrial proteins (Probable).
Target Subcellular Location
Nucleus, nucleoplasm. Mitochondrion matrix. Nucleus, nucleolus.
Target Protein Families
UPF0160 (MYG1) family
Target Tissue Specificity
Ubiquitously expressed, with highest levels in testis.
Target Synonyms
C12orf10; UPF0160 protein MYG1; mitochondrial
Target Background
Predicted to enable nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to act upstream of or within locomotory exploration behavior. Located in mitochondrion and nucleoplasm.
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