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The antibody against CAPZA2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CAPZA2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09910A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPZA2 |
| Target Synonyms | CAPZ; CAPPA2; CAPZA2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, 22Rv1, Mouse brain, THP-1 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P47755 | Immunogen Sequence |
Uniprot Id
P47755
Target Species
Human
Target Name
CAPZA2
Target Full Name
F-actin-capping protein subunit alpha-2
Target Function
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Target Protein Families
F-actin-capping protein alpha subunit family
Target Research Area
Signal Transduction
Target Synonyms
CAPPA2 ; Capping protein (actin filament) muscle Z line; alpha 2 ; CapZ alpha 2; CapZ alpha-2; CAPZ; CAPZA2; CAZA2_HUMAN; F actin capping protein alpha 2 subunit; F actin capping protein subunit alpha 2; F-actin-capping protein subunit alpha-2
Target Background
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end.
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