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The antibody against CD200 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-232 of human CD200 (NP_001352780.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CD200 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-232 of human CD200 (NP_001352780.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-14546A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD200 |
| Target Synonyms | MRC; MOX1; MOX2; OX-2; CD200 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | SH-SY5Y | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 31-232 of human CD200 (NP_001352780.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P41217 | Immunogen Sequence |
Uniprot Id
P41217
Target Species
Human
Target Name
CD200
Target Full Name
OX-2 membrane glycoprotein
Target Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Research Area
Cardiovascular
Target Synonyms
CD200; MOX1; MOX2; My033; OX-2 membrane glycoprotein; CD antigen CD200
Target Background
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
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