Rabbit anti-Human Cdx1 Monoclonal Antibody

The antibody against Cdx1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13244A

Number

Cat.No	ADA-13244A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	CDX1
Form	Liquid	Species Reactivity	Human
Isotype	IgG	Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.
Purification Method	Affinity purification	Positive Samples	HT-29, SGC-7901
Application	ELISA, WB

Cat.No

ADA-13244A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

CDX1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HT-29, SGC-7901

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902).	Target Species	Human
Immunogen Sequence	MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSP	Uniprot ID	P47902

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902).

Target Species

Human

Immunogen Sequence

MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSP

Uniprot ID

P47902

Background Information

Uniprot Id

P47902
Target Species

Human
Target Name

CDX1
Target Full Name

Homeobox protein CDX-1
Target Function

Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.
Target Subcellular Location

Nucleus.
Target Protein Families

Caudal homeobox family
Target Tissue Specificity

Intestinal epithelium.
Target Synonyms

Caudal type homeo box transcription factor 1 ; Caudal type homeobox 1; Caudal type homeobox protein ; Caudal type homeobox protein CDX1; Caudal type homeobox transcription factor 1; Caudal-type homeobox protein 1; CDX1; CDX1_HUMAN; Homeobox protein CDX 1; Homeobox protein CDX-1; MGC116915; OTTHUMP00000160524
Target Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

Rabbit anti-Human Cdx1 Monoclonal Antibody

Specifications

Immunogen Information

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