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The antibody against CFHR3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CFHR3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01951A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CFHR3 |
| Target Synonyms | FHR3; HLF4; CFHL3; FHR-3; DOWN16; CFHR3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat liver | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | AVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQ | Uniprot ID | Q02985 |
Uniprot Id
Q02985
Target Species
Human
Target Name
CFHR3
Target Full Name
Complement factor H-related protein 3
Target Function
Might be involved in complement regulation.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Expressed by the liver and secreted in plasma.
Target Synonyms
FHR3; HLF4; CFHL3; FHR-3; DOWN16; CFHR3
Target Background
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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