Rabbit anti-Human CLSTN3 Polyclonal Antibody

The antibody against CLSTN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 730-850 of human CLSTN3 (NP_055533.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10058A

Number

Cat.No	ADA-10058A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CLSTN3
Target Synonyms	CSTN3; CDHR14; alcbeta; CLSTN3	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain	Application	ELISA, WB

Cat.No

ADA-10058A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CLSTN3

Target Synonyms

CSTN3; CDHR14; alcbeta; CLSTN3

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 730-850 of human CLSTN3 (NP_055533.2).	Target Species	Human
Immunogen Sequence	SLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHRNSMIPSAATL	Uniprot ID	Q9BQT9

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 730-850 of human CLSTN3 (NP_055533.2).

Target Species

Human

Immunogen Sequence

SLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHRNSMIPSAATL

Uniprot ID

Q9BQT9

Background Information

Uniprot Id

Q9BQT9
Target Species

Human
Target Name

CLSTN3
Target Full Name

Calsyntenin-3
Target Function

May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell junction, synapse, postsynapse. Cell projection, dendrite.
Target Tissue Specificity

According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant expression in brain, and only marginal in kidney. In brai
Target Synonyms

CLSTN3; CS3; KIAA0726Calsyntenin-3; Alcadein-beta; Alc-beta
Target Background

Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within several processes, including chemical synaptic transmission; positive regulation of protein localization to synapse; and synapse assembly. Predicted to be located in postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane.

Rabbit anti-Human CLSTN3 Polyclonal Antibody

Specifications

Immunogen Information

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