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The antibody against CNOT10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CNOT10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02214A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNOT10 |
| Target Synonyms | CNOT10 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-431, LO2, Mouse testis, Mouse thymus, NCl-H460 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 465-744 of human CNOT10 (NP_056257.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H9A5 | Immunogen Sequence |
Uniprot Id
Q9H9A5
Target Species
Human
Target Name
CNOT10
Target Full Name
CCR4-NOT transcription complex subunit 10
Target Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
CNOT10 family
Target Synonyms
CNOT10CCR4-NOT transcription complex subunit 10
Target Background
Predicted to be involved in mRNA catabolic process and negative regulation of translation. Located in membrane. Part of CCR4-NOT complex.
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