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The antibody against COG6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 508-657 of human COG6 (NP_065802.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against COG6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 508-657 of human COG6 (NP_065802.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06449A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COG6 |
| Target Synonyms | COD2; SHNS; CDG2L; COG6 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-549, Jurkat, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 508-657 of human COG6 (NP_065802.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MKTTLALFEFTDRRLEMLQFQIEAHLDTLINEQASYVLTRVGLSYIYNTVQQHKPEQGSLANMPNLDSVTLKAAMVQFDRYLSAPDNLLIPQLNFLLSATVKEQIVKQSTELVCRAYGEVYAAVMNPINEYKDPENILHRSPQQVQTLLS | Uniprot ID | Q9Y2V7 |
Uniprot Id
Q9Y2V7
Target Species
Human
Target Name
COG6
Target Full Name
Conserved oligomeric Golgi complex subunit 6
Target Function
Required for normal Golgi function.
Target Involvement
Congenital disorder of glycosylation 2L (CDG2L); Shaheen syndrome (SHNS)
Target Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein.
Target Protein Families
COG6 family
Target Synonyms
COD2; SHNS; CDG2L; COG6
Target Background
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.
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