Rabbit anti-Human CRALBP Monoclonal Antibody

The antibody against CRALBP was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRALBP (P12271) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-14027A

Number

Cat.No	ADA-14027A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	CRALBP
Target Synonyms	CRALBP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse eye	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-14027A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

CRALBP

Target Synonyms

CRALBP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse eye

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRALBP (P12271).	Target Species	Human
Immunogen Sequence	MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFI	Uniprot ID	P12271

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CRALBP (P12271).

Target Species

Human

Immunogen Sequence

MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFI

Uniprot ID

P12271

Background Information

Uniprot Id

P12271
Target Species

Human
Target Name

RLBP1
Target Full Name

Retinaldehyde-binding protein 1
Target Function

Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.
Target Involvement

Bothnia retinal dystrophy (BRD); Rod-cone dystrophy Newfoundland (NFRCD); Retinitis punctata albescens (RPA)
Target Subcellular Location

Cytoplasm.
Target Tissue Specificity

Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina.
Target Research Area

Others
Target Synonyms

Cellular retinaldehyde binding protein 1; Cellular retinaldehyde binding protein; Cellular retinaldehyde-binding protein; MGC3663; Retinaldehyde binding protein 1; Retinaldehyde-binding protein 1; RLBP 1; RLBP1; RLBP1_HUMAN
Target Background

The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.

Rabbit anti-Human CRALBP Monoclonal Antibody

Specifications

Immunogen Information

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