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Rabbit anti-Human CREG1 Polyclonal Antibody

The antibody against CREG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human CREG1 (NP_003842.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04649A

The antibody against CREG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human CREG1 (NP_003842.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04649A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCREG1
Target SynonymsCREG; CREG1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesK-562ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 110-190 of human CREG1 (NP_003842.1).Target SpeciesHuman
Immunogen SequenceLQLSVSNLQENPYATLTMTLAQTNFCKKHGFDPQSPLCVHIMLSGTVTKVNETEMDIAKHSLFIRHPEMKTWPSSHNWFFAUniprot IDO75629
Background Information
  • Uniprot Id

    O75629

  • Target Species

    Human

  • Target Name

    CREG1

  • Target Full Name

    Protein CREG1

  • Target Function

    May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    CREG family

  • Target Synonyms

    Cellular repressor of E1A stimulated genes 1; Cellular repressor of E1A-stimulated genes 1; CREG; CREG1; CREG1_HUMAN; Protein CREG1

  • Target Background

    The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

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