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The antibody against CTNNBL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CTNNBL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTNNBL1 |
| Target Synonyms | NAP; P14L; IMD99; PP8304; C20orf33; dJ633O20.1; CTNNBL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, HepG2, Jurkat, Mouse thymus, SW620 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WYA6 | Immunogen Sequence |
Uniprot Id
Q8WYA6
Target Species
Human
Target Name
CTNNBL1
Target Full Name
Beta-catenin-like protein 1
Target Function
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.
Target Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.
Target Tissue Specificity
Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.
Target Synonyms
5730471K09Rik; Beta catenin like 1; Beta catenin like protein 1; Beta-catenin-like protein 1; C20orf33; Cadherin associated protein; Catenin beta like 1; Chromosome 20 open reading frame 3; CTBL1_HUMAN; CTNN protein; CTNNBL 1; Ctnnbl1; dJ633O20.1; FLJ21108; NAP; Nuclear associated protein; nuclear protein NAP; Nuclear-associated protein; NYD SP19; OTTMUSP00000016933; P14; P14L; PP8304; RP5 1118M15.1; Testis development protein NYD SP19; Testis development protein NYD-SP19
Target Background
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.
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