Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against DCK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against DCK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-09955A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DCK |
| Target Synonyms | DCK | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293F, Mouse brain, Rat liver | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P27707 | Immunogen Sequence |
Uniprot Id
P27707
Target Species
Human
Target Name
DCK
Target Full Name
Deoxycytidine kinase
Target Function
Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Target Subcellular Location
Nucleus.
Target Protein Families
DCK/DGK family
Target Research Area
Cancer
Target Synonyms
dCK; DCK protein; DCK_HUMAN; Deoxycytidine kinase; Deoxynucleoside kinase; EC 2.7.1; EC 2.7.1.74; MGC117410; MGC138632; OTTHUMP00000219118; OTTHUMP00000219119
Target Background
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
