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The antibody against DDX46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 682-1031 of human DDX46 (NP_055644.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against DDX46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 682-1031 of human DDX46 (NP_055644.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-08631A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DDX46 |
| Target Synonyms | Prp5; PRPF5; DDX46 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Mouse testis, Rat testis | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 682-1031 of human DDX46 (NP_055644.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q7L014 | Immunogen Sequence |
Uniprot Id
Q7L014
Target Species
Human
Target Name
DDX46
Target Full Name
Probable ATP-dependent RNA helicase DDX46
Target Function
Plays an essential role in splicing, either prior to, or during splicing A complex formation.
Target Subcellular Location
Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid-anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.
Target Protein Families
DEAD box helicase family, DDX46/PRP5 subfamily
Target Synonyms
DDX46; KIAA0801Probable ATP-dependent RNA helicase DDX46; EC 3.6.4.13; DEAD box protein 46; PRP5 homolog
Target Background
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene.
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