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The antibody against DESI2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human DESI2 (NP_057160.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DESI2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human DESI2 (NP_057160.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02185A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DESI2 |
| Target Synonyms | DESI; DESI1; DeSI-2; PNAS-4; PPPDE1; CGI-146; FAM152A; C1orf121; DESI2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human DESI2 (NP_057160.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASVASTAAGSRPGRHTKL | Uniprot ID | Q9BSY9 |
Uniprot Id
Q9BSY9
Target Species
Human
Target Name
DESI2
Target Full Name
Deubiquitinase DESI2
Target Function
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
Target Subcellular Location
Cytoplasm.
Target Protein Families
DeSI family
Target Synonyms
DESI2; C1orf121; FAM152A; PPPDE1; CGI-146; PNAS-4; Deubiquitinase DESI2; EC 3.4.19.12; Desumoylating isopeptidase 2; DeSI-2; PPPDE peptidase domain-containing protein 1; Protein FAM152A
Target Background
Enables Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to be located in cytoplasm.
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