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The antibody against DNAAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 516-725 of human DNAAF1 (NP_848547.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DNAAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 516-725 of human DNAAF1 (NP_848547.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00180A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DNAAF1 |
| Target Synonyms | swt; DAU1; ODA7; CILD13; LRRC50; DNAAF1 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 516-725 of human DNAAF1 (NP_848547.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8NEP3 | Immunogen Sequence |
Uniprot Id
Q8NEP3
Target Species
Human
Target Name
DNAAF1
Target Full Name
Dynein axonemal assembly factor 1
Target Function
Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
Target Involvement
Ciliary dyskinesia, primary, 13 (CILD13)
Target Subcellular Location
Cell projection, cilium. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=In HEK293T cells, it is diffusely cytoplasmic and concentrates at the mitotic spindle poles, while in MDCK cells, it localizes in the cilium. In vivo, this protein is probably restricted to the cilium.
Target Protein Families
DNAAF1 family
Target Tissue Specificity
Mainly expressed in trachea and testis.
Target Synonyms
DNAAF1; LRRC50Dynein assembly factor 1; axonemal; Leucine-rich repeat-containing protein 50
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