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Rabbit anti-Human DSG4 Polyclonal Antibody

The antibody against DSG4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01604A

The antibody against DSG4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01604A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDSG4
Target SynonymsLAH; HYPT6; CDGF13; CDHF13; DSG4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-375, BxPC-3, DU145, Mouse pancreas, Mouse small intestine, Rat pancreasApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1).Target SpeciesHuman
Immunogen SequenceTGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPUniprot IDQ86SJ6
Background Information
  • Uniprot Id

    Q86SJ6

  • Target Species

    Human

  • Target Name

    DSG4

  • Target Full Name

    Desmoglein-4

  • Target Function

    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes.

  • Target Involvement

    Hypotrichosis 6 (HYPT6)

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

  • Target Tissue Specificity

    Highly expressed in skin, testis and prostate; less in salivary gland. In scalp follicles, present in the inner root sheath (IRS) and all layers of the matrix and precortex.

  • Target Synonyms

    DSG4; CDHF13; Desmoglein-4; Cadherin family member 13

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