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The antibody against ELMO3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 504-773 of human ELMO3 (NP_078988.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ELMO3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 504-773 of human ELMO3 (NP_078988.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02643A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELMO3 |
| Target Synonyms | CED12; CED-12; ELMO-3; ELMO3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 22Rv1, HT-29, Mouse brain, Mouse liver, Rat lung, SW480 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 504-773 of human ELMO3 (NP_078988.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96BJ8 | Immunogen Sequence |
Uniprot Id
Q96BJ8
Target Species
Human
Target Name
ELMO3
Target Full Name
Engulfment and cell motility protein 3
Target Function
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Target Subcellular Location
Cytoplasm.
Target Synonyms
CED 12; Ced 12 homolog 3; CED12; ELMO 3; ELMO3; ELMO3_HUMAN; Engulfment and cell motility 3; Engulfment and cell motility protein 3; FLJ13824
Target Background
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.
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