Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against EML4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human EML4 (NP_061936.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against EML4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human EML4 (NP_061936.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-04630A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EML4 |
| Target Synonyms | C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120; EML4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2 | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 360-560 of human EML4 (NP_061936.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9HC35 | Immunogen Sequence |
Uniprot Id
Q9HC35
Target Species
Human
Target Name
EML4
Target Full Name
Echinoderm microtubule-associated protein-like 4
Target Function
Essential for the formation and stability of microtubules (MTs). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs. Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center. Midbody.
Target Protein Families
WD repeat EMAP family
Target Synonyms
EML4; C2orf2; Echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; ELP 120; ELP120; EMAL4_HUMAN; EMAP 4; EMAP-4; EMAP4; EML 4; eml4; Restrictedly overexpressed proliferation associated protein; Restrictedly overexpressed proliferation-associated protein; Ropp 120; ROPP120
Target Background
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
