Rabbit anti-Human EPN2 Polyclonal Antibody

The antibody against EPN2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_683723.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-04637A

Number

Cat.No	ADA-04637A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	EPN2
Target Synonyms	EHB21; EPN2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, LO2, U-87MG	Application	ELISA, WB, IHC-P

Cat.No

ADA-04637A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

EPN2

Target Synonyms

EHB21; EPN2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, LO2, U-87MG

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_683723.2).	Target Species	Human
Immunogen Sequence	GINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPS	Uniprot ID	O95208

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_683723.2).

Target Species

Human

Immunogen Sequence

GINVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTSHSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKIPKKKEHGSLPQQTTLLDLMDALPSSGPAAQKAEPWGPS

Uniprot ID

O95208

Background Information

Uniprot Id

O95208
Target Species

Human
Target Name

EPN2
Target Full Name

Epsin-2
Target Function

Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Target Subcellular Location

Cytoplasm. Cytoplasmic vesicle, clathrin-coated vesicle. Note=In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
Target Protein Families

Epsin family
Target Tissue Specificity

Highest expression is found in brain. Detected at lower levels in lung and liver.
Target Synonyms

EHB21; EPN 2; Epn2; EPN2_HUMAN; EPS 15 interacting protein 2; EPS-15-interacting protein 2; Eps15 binding protein; Epsin 2; Epsin-2; Epsin2; KIAA1065; OTTHUMP00000065808; OTTHUMP00000065809; OTTHUMP00000065810; OTTHUMP00000065811; OTTHUMP00000065889
Target Background

Predicted to enable clathrin binding activity and phospholipid binding activity. Acts upstream of or within Notch signaling pathway; embryonic organ development; and in utero embryonic development. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of clathrin coat of endocytic vesicle. Predicted to be active in endosome and plasma membrane. Orthologous to human EPN2 (epsin 2).

Rabbit anti-Human EPN2 Polyclonal Antibody

Specifications

Immunogen Information

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