Rabbit anti-Human F2RL3 Polyclonal Antibody

The antibody against F2RL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human F2RL3 (NP_003941.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08995A

Number

Cat.No	ADA-08995A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	F2RL3
Target Synonyms	PAR4; F2RL3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, B cells, HT-29, Mouse lung, Mouse skeletal muscle, Mouse spleen, Raji, Rat spleen	Application	ELISA, WB

Cat.No

ADA-08995A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

F2RL3

Target Synonyms

PAR4; F2RL3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, B cells, HT-29, Mouse lung, Mouse skeletal muscle, Mouse spleen, Raji, Rat spleen

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human F2RL3 (NP_003941.2).	Target Species	Human
Immunogen Sequence	TQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACR	Uniprot ID	Q96RI0

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human F2RL3 (NP_003941.2).

Target Species

Human

Immunogen Sequence

TQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACR

Uniprot ID

Q96RI0

Background Information

Uniprot Id

Q96RI0
Target Species

Human
Target Name

F2RL3
Target Full Name

Proteinase-activated receptor 4
Target Function

Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.
Target Synonyms

F2RL3; PAR4; Proteinase-activated receptor 4; PAR-4; Coagulation factor II receptor-like 3; Thrombin receptor-like 3
Target Background

This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.

Rabbit anti-Human F2RL3 Polyclonal Antibody

Specifications

Immunogen Information

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