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Rabbit anti-Human FAM120A Polyclonal Antibody

The antibody against FAM120A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07001A

The antibody against FAM120A was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07001A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFAM120A
Target SynonymsOSSA; C9orf10; HBVPTPAP; FAM120AFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human FAM120A (NP_055427.2).Target SpeciesHuman
Immunogen SequenceMGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPUniprot IDQ9NZB2
Background Information
  • Uniprot Id

    Q9NZB2

  • Target Species

    Human

  • Target Name

    FAM120A

  • Target Full Name

    Constitutive coactivator of PPAR-gamma-like protein 1

  • Target Function

    May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.

  • Target Protein Families

    Constitutive coactivator of PPAR-gamma family

  • Target Tissue Specificity

    Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).

  • Target Synonyms

    C9orf10; Chromosome 9 open reading frame 10; Constitutive coactivator of PPAR gamma like protein 1; Constitutive coactivator of PPAR-gamma-like protein 1; DNA polymerase transactivated protein 5; DNA polymerase transactivated protein 1; DNAPTP1; DNAPTP5; F120A_HUMAN; FAM120A; Family with sequence similarity 120A; Hypothetical protein LOC23196; KIAA0183; LOC23196; MGC111527; MGC133257; OSSA; Oxidative stress-associated Src activator; Protein FAM120A

  • Target Background

    Enables RNA binding activity. Located in cytosol.

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