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The antibody against FKBP10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human FKBP10(NP_068758.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FKBP10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human FKBP10(NP_068758.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
Western blot analysis of lysates from HeLa cells, using FKBP10 Rabbit pAb at 1:2000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 180s.
| Cat.No | ADA-08174A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FKBP10 |
| Target Synonyms | FKBP10; BRKS1; FKBP65; OI11; OI6; PPIASE; hFKBP65; FK506 binding protein 10 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 303-582 of human FKBP10(NP_068758.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96AY3 | Immunogen Sequence |
Uniprot Id
Q96AY3
Target Species
Human
Target Name
FKBP10
Target Full Name
Peptidyl-prolyl cis-trans isomerase FKBP10
Target Function
PPIases accelerate the folding of proteins during protein synthesis.
Target Involvement
Osteogenesis imperfecta 11 (OI11); Bruck syndrome 1 (BRKS1)
Target Subcellular Location
Endoplasmic reticulum lumen.
Target Synonyms
FKBP10; FKBP65; PSEC0056Peptidyl-prolyl cis-trans isomerase FKBP10; PPIase FKBP10; EC 5.2.1.8; 65 kDa FK506-binding protein; 65 kDa FKBP; FKBP-65; FK506-binding protein 10; FKBP-10; Immunophilin FKBP65; Rotamase
Target Background
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.
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