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The antibody against FRAT1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FRAT1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04643A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FRAT1 |
| Target Synonyms | FRAT1 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse spleen, Mouse thymus, Rat spleen, Rat testis | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human FRAT1 (NP_005470.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | HRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS | Uniprot ID | Q92837 |
Uniprot Id
Q92837
Target Species
Human
Target Name
FRAT1
Target Full Name
Proto-oncogene FRAT1
Target Function
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
GSK-3-binding protein family
Target Synonyms
FRAT1Proto-oncogene FRAT1; Frequently rearranged in advanced T-cell lymphomas 1; FRAT-1
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