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The antibody against FUT8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against FUT8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03341A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FUT8 |
| Target Synonyms | CDGF; CDGF1; FUT8 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_835367.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | FHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK | Uniprot ID | Q9BYC5 |
Uniprot Id
Q9BYC5
Target Species
Human
Target Name
FUT8
Target Full Name
Alpha-(1,6)-fucosyltransferase
Target Function
Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
Target Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 23 family
Target Synonyms
6-fucosyltransferase; Alpha (1,6) fucosyltransferase; Alpha-(1,6)-fucosyltransferase; Alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8 (alpha (1,6) fucosyltransferase) ; Fucosyltransferase 8; FUT8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,6 fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1; Glycoprotein 6 alpha L fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; MGC26465
Target Background
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
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